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Brefeldin A, ≥99%

Catalog No. 517177

General Information
SynonymsAscotoxin, BFA, Cyanein, Decumbin
CAS No.20350-15-6


Beilstein No.25191
MDL No.MFCD12913297
Technical Data
AppearanceWhite to off-white crystalline powder
Melting Point (°C)199-204℃
Purity≥99% HPLC
SolubilityDMSO, Ethanol, Methanol
DescriptionBrefeldin A (BFA) is a reversible inhibitor of protein translocation from the endoplasmic reticulum (ER) to the Golgi apparatus. It blocks binding of ADP-ribosylation factor to the Golgi apparatus and inhibits GDP-GTP exchange. It can be used to induce autophagy in mammalian cells.

Kim S, et al. PLoS One. 2013 Dec 13;8(12):e81978
Colanzi A, et al. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9794-9
Vicetti Miguel RD, et al. J Immunol Methods. 2012 Oct 31;384(1-2):191-5
Schuerwegh AJ, et al Cytometry. 2001 Jun 15;46(3):172-6
Alvarez C, et al. Eur J Cell Biol. 1999 Jan;78(1):1-14

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25 mg USD68
100 mg USD208
500 mg USD728

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