LANCRIX

SB 431542, ≥98%

Catalog No. 411114

Identification
CAS No.301836-41-9
M.F.

C22H16N4O3

M.W.384.39
MDL No.MFCD05865244
PubChem Substance ID136340199
Technical Data
AppearanceWhite solid
Purity≥98% HPLC
SolubilityDMSO, Ethanol
Storage-20℃
ApplicationSB 431542 is a known Src family kinase inhibitor that effectively blocks the transforming growth factor-β1-induced cell migration and invasion in both established and primary carcinoma cells.
Safety Data
Reference

Rico-Leo EM, et al. J Biol Chem. 288(11):7841-56, (2013)
Kim YJ, et al. Anticancer Res. 32(3):799-806, (2012)
Tobias, B., et al.: Cancer. Chemother. Pharmacol., 70, 221 (2012)
James, J., et al.: Molec. Cancer. Therap., 11, 930 (2012)
Morales MG, et al. Int J Biochem Cell Biol. 44(11):1993-2002, (2012)
Wang QL, et al. Zhong Xi Yi Jie He Xue Bao, 10(5):561-8, (2012)
Suson KD, et al. J Urol. 188(4 Suppl):1528-33, (2012)
Ma Q, et al. Mol Cancer. 10:66, (2011)
Waghabi MC, et al. Antimicrob Agents Chemother. 51(8):2905-10, (2007)

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