LANCRIX

Afatinib, ≥99%

Catalog No. 556853

Identification
SynonymsBIBW2992
CAS No.439081-18-2
M.F.

C24H25ClFN5O3

M.W.485.94
Technical Data
AppearanceOff-white powder
Assay≥99% HPLC
SolubilityDMSO
Storage-20℃
ApplicationAfatinib irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2.
Safety Data
Reference

Passaro A, et al. J Thorac Dis. 2013 Aug;5(4):383-4
Yap TA, et al. Expert Opin Drug Metab Toxicol. 2013 Aug 28. [Epub ahead of print]
Wang W, et al. Clin Cancer Res. 2012 Mar 15;18(6):1663-71
Gong HC, et al. Int J Proteomics. 2011;2011:215496

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