LANCRIX

BINA, ≥98%

Catalog No. 237547

Identification
SynonymsBiphenyl-indanone A
CAS No.866823-73-6
M.F.

C30H30O4

M.W.454.56
MDL No.MFCD19440914
Technical Data
AppearanceOff-white powder
Assay≥98% HPLC
SolubilityDMSO
Storage-20℃
ApplicationBINA is a selective positive allosteric modulator of mGlu2. It displays no effect on glutamate-induced activation of other mGlu receptor subtypes. It exhibits antipsychotic and anxiolytic properties in mice.
Safety Data
Reference

Sanger H, et al. Neuropharmacology. 2013 Mar;66:264-73
Hackler EA, et al. Neuroscience. 2010 Jun 16;168(1):209-18
Hemstapat K, et al. J Pharmacol Exp Ther. 2007 Jul;322(1):254-64
Benneyworth MA, et al. Mol Pharmacol. 2007 Aug;72(2):477-84
Galici R, et al. J Pharmacol Exp Ther. 2006 Jul;318(1):173-85

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