LANCRIX

Leflunomide, ≥99%

Catalog No. 758453

Identification
Synonyms5-Methylisoxazole-4-(4-trifluoromethyl)carboxanilide
CAS No.75706-12-6
M.F.

C12H9F3N2O2

M.W.270.21
MDL No.MFCD00867593
PubChem Substance ID24278516
Technical Data
AppearanceWhite or off-white crystalline powder
Melting Point (°C)164-168℃
Assay≥99%
Solubility Dichloromethane, Ether, Ethyl Acetate, Methanol
StorageProtected from light
ApplicationBy virtue of its immunosuppressant effects, leflunomide has found use in organ transplantation and treatment of rheumatoid arthritis and other autoimmune diseases.
Safety Data
SymbolGHS06
Hazard StatementsH301-H315-H319-H335
Precautionary StatementsP261-P301 + P310-P305 + P351 + P338
WGK Germany3
RTECSNY2354200
Reference

Davies, M., et al.: J. Med. Chem., 52, 2683 (2009)
Vrenken, T., et al.: J. Hepatol., 49, 799 (2008)
Mazzucco, G., et al.: Clin. Nephrol., 70, 163 (2008)

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