LANCRIX

Lubiprostone, ≥99%

Catalog No. 183573

Identification
Synonyms(11α)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid; Ru 0211
CAS No.136790-76-6
M.F.

C20H32F2O5

M.W.390.46
Technical Data
AppearanceWhite crystal or crystalline powder
Purity≥99% HPLC
SolubilityChloroform
Storage-20℃
ApplicationLubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.
Safety Data
Reference

Farthing, M., et al.: Drugs, 56, 11 (1998)
Pare, P., et al.: Am. J. Gastroenterol., 96, 3130 (2001)
Sloots, C., et al.: Aliment. Pharmacol. Ther., 16, 759 (2002)
Coremans, G., et al.: Digestion, 67, 82 (2003)

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